What is the Depo-Provera Lawsuit? Latest Litigation Updates

Are you or a loved one one of the many individuals who used the birth-control shot Depo‑Provera and later experienced serious health problems? There have been several new developments in ongoing litigation against the manufacturers of the Depo-Provera shot.

The defective product attorneys of Portner & Shure, P.A. are up to date on all of the latest litigation updates and can help you pursue compensation if you have been affected by the Depo-Provera shot.

Current Status of Depo-Provera Litigation in 2025

In February 2025, the Judicial Panel on Multidistrict Litigation (JPML) ordered consolidation of federal lawsuits under a multidistrict litigation (MDL) that Depo-Provera and its generic equivalents caused certain health injuries.

Since consolidation, the number of cases has grown significantly. While some earlier reports put the case count in the low hundreds, recent sources indicate more than 1,200 individual lawsuits have been filed as of October 2025.

Key developments:

• The MDL is in the Northern District of Florida, before Judge M. Casey Rodgers.
• Case Management Order No. 1 and other orders establish deadlines for discovery and proof of use/injury questionnaires.
• Plaintiffs are required to provide proof of injection and health injury data, including medical records and pharmacy/insurance/distributor records.
• A pivotal legal issue is the so-called “preemption” defense raised by the manufacturer, arguing that federal law (via the Food & Drug Administration) precludes state-law failure-to-warn claims.

What this means for those seeking restitution is that litigation is still in the pretrial and discovery phase. This phase could go on for some time as data is discovered and revealed. Studies will be looked at by both plaintiff and defendant. No large mass settlement has been announced to date. 

If you used Depo-Provera and later developed a qualifying health injury, you may still have time to join the MDL. The attorneys at Portner & Shure, P.A. can evaluate your claim and make sure you are an active participant in any class actions to ensure you receive compensation for your injuries suffered after using Depo-Provera.

Understanding Depo-Provera and Associated Health Risks

Depo‑Provera is an injectable contraceptive whose active ingredient is depot medroxyprogesterone acetate (DMPA). It has been used for decades as a long-acting birth control option.

Why These Health Risks Have Led to Widespread Litigation

Although Depo-Provera was approved for contraceptive use, plaintiffs in the MDL allege that prolonged or repeated injections caused serious health injuries, such as:

• Brain tumors called meningiomas (tumors of the membranes covering the brain and spinal cord)
• Infertility or impaired fertility
• Significant bone density loss (osteoporosis risk)

These injuries and their link to Depo-Provera are the basis for the MDL lawsuits. New studies have brought to light just how damaging these shots may be. For example, a French study found a 5.6-fold increased risk of meningioma with certain progestogen contraceptives. 

Manufacturers and defendants dispute causation or warning liability, which is why the consolidation and litigation process is underway.

What Types of Injuries Are Covered in the Depo-Provera Lawsuits?

While each case is unique, the predominant claims in this litigation involve:

• Diagnosis of meningioma brain or spinal tumors after using Depo-Provera or generic DMPA injections.
• Evidence that the individual used Depo-Provera for extended periods and developed symptoms consistent with tumor growth, surgery, neurological damage, or related complications.
• Claims of failure to warn alleging the manufacturer did not adequately alert healthcare providers or patients to these risks.
• Some cases include infertility or bone density claims, though the primary wave is the tumor litigation.

If you were diagnosed with a meningioma (or related brain/spinal tumor) after using Depo-Provera, you might qualify for a claim under the MDL.

How Portner & Shure, P.A. Can Help

At Portner & Shure, P.A., our trial-attorneys are experienced in handling complex product-liability and medical malpractice claims in Maryland, Virginia, North Carolina, Kentucky, and Washington, D.C. We understand the debilitating nature of the symptoms prolonged use of Depo-Provera can cause, and that our clients want justice above all else for the harm caused to them.

If you believe you may be eligible for a Depo-Provera lawsuit, we offer a free, no-obligation review of your case.

We can help you:

• Determine whether your Depo-Provera usage and injury history meet the criteria for the MDL.
• Gather and preserve the necessary medical records, pharmacy or distributor records, and proof of use/injury materials.
• Coordinate with national counsel in the MDL and protect your rights.
• Negotiate on your behalf or prepare for potential trial outcomes, seeking maximum compensation for your medical expenses, pain and suffering, lost earnings, and more.

Taking action now is critical, because once deadlines pass or relevant records are lost, your ability to claim may be compromised.

Contact us today at (410) 995-1515 for a consultation and let one of our Depo-Provera lawsuit lawyers help you seek the compensation you need.

Frequently Asked Questions (FAQs)

Who can file a Depo-Provera lawsuit?

Any individual who used Depo-Provera (or a generic DMPA injection) and later suffered a qualifying health injury, especially a diagnosed meningioma, may be eligible. Each case is individual; eligibility depends on your medical history, usage timeline, and jurisdiction.

What compensation might be available?

Compensation may cover medical bills, future care costs, lost wages, pain and suffering, and other damages. Qualifying cases may participate in the MDL or pursue individual claims.

How long does the litigation process take?

Product-liability MDLs often move slowly, as discovery, expert reports, and case-management orders must be completed first. Some early “pilot” cases or bellwether trials may set precedents. Others remain pending for years.

Is there a class action or individual lawsuit option?

There is not a class-action lawsuit for Depo-Provera. Instead, the cases are consolidated in a multidistrict litigation (MDL) where individual claims are grouped for pretrial matters but remain separate. 

How do I start a claim with Portner & Shure, P.A.?

Call us or submit your information online to schedule a confidential consultation. We will review your use of Depo-Provera, discuss your injuries and medical history, and advise whether you may join the MDL or file a claim in your state or federal court.