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Invokana (canagliflozin) is a prescription drug manufactured by Johnson & Johnson to treat those with type 2 diabetes and was approved by the FDA in 2013. Since then, Invokana became very popular, especially as the number of people diagnosed with diabetes rose. Although, numerous cases of serious side-effects emerged from those who have taken the drug, including kidney failure and diabetic ketoacidosis.

At Portner & Shure, P.A. Attorneys at Law, our experienced drug injury lawyers want those with type 2 diabetes to understand the risks and health complications that may come from taking this drug and to help those who have suffered as a result of using this medication.

If you've experienced serious side-effects or any health-related issues from taking Invokana, contact us today at one of our offices in Maryland at 410-995-1515 or 301-854-9000, in Virginia at (703) 734-8790, or in Washington, D.C. at 202-554-1449 for your free consultation. Your case may be eligible for mass tort litigation. The mass tort attorneys at Portner & Shure are committed to providing effective, aggressive legal representation to clients from Washington D.C., Baltimore, and counties throughout Maryland, Northern Virginia, and Richmond.

What is Invokana?

Invokana is a sodium-glucose cotransporter-2 (SGLT2) inhibitor prescribed to people with type 2 diabetes. Its function is to help lower blood sugar and improve glycemic control. The drug is designed to lower blood glucose levels by inhibiting some kidney functions. Invokana is the only type 2 diabetes drug that uses the kidneys and allows a high level of glucose to enter the kidneys. It works by causing blood sugar to leave the body through urine.

Lawsuits have been filed against Johnson & Johnson, the manufacturer of Invokana, arguing that they withheld risks of kidney failure, diabetic ketoacidosis, and heart attacks from users of the drug. In 2015, the FDA required Johnson & Johnson to include warnings about these serious side effects.

Invokana Side-Effects and Their Symptoms

Since Invokana has been on the market, numerous reports of complications and serious side-effects have occurred. Read below to learn more about the serious health issues that may occur if you take Invokana and the symptoms they present.


One of the most severe side-effects of taking Invokana is the potential to develop diabetic ketoacidosis (DKA). This is a severe diabetes complication in which excess blood acids are produced when there isn't enough insulin in the body. People with this condition may need to be hospitalized, which can lead to life-threatening health complications. Symptoms of ketoacidosis include:

  • Nausea
  • Vomiting
  • Abdominal pain
  • Trouble breathing
  • Confusion
  • Difficulty concentrating
  • Fatigue
  • Dry or flushed skin

Kidney Failure

The kidneys play an essential part in keeping the body healthy. Because of their role in filtering blood by removing waste and also controlling blood pressure, electrolyte balance, and red blood cell production, the kidneys are important for the body’s everyday functioning. Since 2014, Invokana has been linked to kidney failure.

When the kidneys fail, they lose those the abilities to function properly, resulting in waste, fluids, and electrolytes building in the body, which can lead to severe health problems. Symptoms of kidney failure include:

  • Weakness
  • Shortness of breath
  • Exhaustion
  • Confusion
  • Abnormal heart rhythms

In some cases, kidney failure can also cause sudden death. If you or someone you love has been taking Invokana for an extended period of time and have experienced any of these symptoms, contact a doctor immediately.

Heart Disease

There have also been accounts of individuals suffering heart attacks and stroke as a result of taking Invokana. Studies have shown that those who use Invokana had an increased risk of heart attack or stroke within the first 30 days of taking the drug. The risk stems from the rise of hematocrit, which is the concentration of red blood cells. When these levels rise, the risk of blood clots increases which can lead to heart attack or stroke.

Symptoms of heart attack or stroke include:

  • Shortness of breath
  • Chest pain
  • Extreme fatigue
  • Dizziness
  • Nausea
  • Cold sweats
  • Face drooping
  • Arm weakness
  • Speech difficulty


Beginning in 2015 the FDA started issuing warnings related to the side-effects from taking Invokana. And in 2017, after two clinical trials, the FDA issued new warnings stating that taking the drug for a prolonged period of time increased amputation risks by nearly double compared to those who took the placebo in the trials. The numbers the FDA found were that roughly 7.5 of every 1,000 people who took Invokana for type 2 diabetes had a higher risk of lower limb amputation.

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Compensation We Can Pursue

The serious medical complications associated with taking Invokana have prompted many individuals to pursue litigation for damages related to taking the drug. Because of the inadequate warnings from manufacturers, defective product and drug lawyers are fighting on behalf of their clients to seek compensation for the serious side-effects many have experienced.

You may be entitled to compensation if you suffered kidney failure within 45 days of last use of the drug, diabetic ketoacidosis within 15 days of last use, or heart attack within 15 days of last use. We can pursue compensation related to:

  • Medical expenses
  • Rehabilitation bills
  • Lost wages from missed work
  • Pain and suffering
  • Funeral expenses (in the event of wrongful death)

Contact Our Experienced Layers Today

If you've used Invokana to treat type 2 diabetes and experienced any of the above adverse health problems, contact our highly-skilled drug injury lawyers today at one of our offices in Maryland at 410-995-1515 or 301-854-9000, in Virginia at (703) 734-8790, or in Washington, D.C. at 202-554-1449 for your free consultation.

We proudly include Spanish, Vietnamese, Korean, Mandarin Chinese, and Cantonese Chinese speaking paralegals among our dedicated legal team. We welcome clients from Baltimore, counties throughout Maryland, Richmond, and other areas of Virginia and DC.